
Overview
The Depressor anguli oris (= DAO) and the Depressor labii inferioris (DLI) muscles are located in the perioral region and connect the lower lip to the mandible. Understanding that the DAO connects to the corner of the mouth makes this muscle an optimal target muscle when treating a sad facial appearance. However, due to the proximity to the DLI muscle, adverse events are not excluded. Understanding and reviewing the underlying anatomy is crucial for staying safe and effective when treating the perioral region with Neuromodulators. Although no injection simulations are performed, this video is best suited for briefly freshen up on perioral muscular anatomy prior to clinical treatments.
Treatment type: Relevant for Neuromodulator Injections
Facial region: Perioral
Approach: Anatomic Review
Competency Level: Novice
Course duration: 8 minutes
Course type: Anatomy lecture with dissection videos performed by Prof. Sebastian Cotofana
Learning Objectives
- Identify the anatomy and attachments of the DAO and DLI muscles.
- Describe their roles in facial expression and lines.
- Explain the labiomandibular sulcus’s aesthetic importance.
- Analyze their locations to guide safe, targeted treatments.
FAQs
Our online anatomy courses is designed for aesthetic practitioners, including MDs, RNs, PAs, and NPs, as well as medical students, residents, and any healthcare professionals.

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