Cotofana Anatomy
Neuromodulator Treatments: Marionette Line

Neuromodulator Treatments: Marionette Line

Red background

Overview

A sad facial appearance can be treated with neuromodulator injections into the Depressor anguli oris muscle. Upon relaxation of this muscle, the downwards pull of the oral commissure becomes less and the facial elevators can increase their upwards pull resulting a happier facial expression. This video explains how to use the Marinette lines as a reliable clinical landmark to achieve safer and superior clinical outcomes.

Treatment type: Neuromodulators

Facial region: Perioral

Approach: Needle Injection Technique

Competency Level: Competent

Course duration: 9 minutes

Course type: Injection simulation on a human body donor performed by Prof. Sebastian Cotofana

Learning Objectives

  • Describe the anatomy of the Depressor Anguli Oris (DAO).
  • Differentiate between the DAO and Depressor Labii Inferioris (DLI) muscles during treatment.
  • Identify clinical landmarks and the correct injection depth for DAO neuromodulation.
  • Apply appropriate dosage and technique to improve marionette lines safely and effectively.

FAQs

Learners will only have access to the marionette lines course and other online anatomy courses for the duration of their active subscription. You can revisit the videos and materials as often as needed to reinforce your learning while your subscription is active.

black-graphic

Access the full
course library

Unlock the complete Cotofana Anatomy e-learning library with a monthly or annual membership.

red graphic

Empower your
clinical team

Provide your organisation to the e-learning platform with a tailored Corporate Plan.

Buy this lesson

30-day access

Become a member

Get unlimited access

Subscribe & Save
Be the first to know

Be the first to know

Join our community for news, offers, and updates on Cotofana Anatomy’s events and resources

Copyright © 2026. Cotofana Anatomy. All rights reserved.